Toxicity tests in animals: alternative models.
نویسندگان
چکیده
منابع مشابه
Toxicity tests in animals: alternative models.
The assessment of chromosomal mutations in children may provide information about aetiology and risk of second malignancies. A somatic cell mutation assay which determines variant erythrocytes lacking expression of an allelic form of the sialoglycoprotein, glycophorin A, was applied to samples from children before and after receiving potentially genotoxic therapy. Fifty-six children who had rec...
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There is increasing interest in the use of microspheres, loaded with chemotherapeutic agents, for regional therapy to hepatic metastases. It is necessary to deliver these particles predominately to tumour rather than to normal liver. This study investigates factors influencing the distribution of regionally injected microspheres. Discreet tumour was induced in rats by subcapsular hepatic inocul...
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*Correspondence: Xiao Huang, Institute of Cellular and Developmental Biology, College of Life Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China e-mail: [email protected]; Huahong Shi, State Key Laboratory of Estuarine and Coastal Research, East China Normal University, 3663 Zhongshan Road (N), Shanghai 200062, China e-mail: [email protected] Organotin compo...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1993
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.93101288